SUBJECT 01
Skin stem cells
The skin protects our bodies from daily wear and tear, harmful microbes, and other assaults from the external environment. Tissue stem cells work to maintain the skin’s function, and restore it after injury.


SUBJECT 02
Regeneration and repair
Stem cells are sentinels of their environment, rapidly adapting their activities to urgent physiological needs. This plasticity allows them to regenerate and repair tissue through the processes of migration, proliferation, metabolism and/or changes in cellular identity .
SUBJECT 03
Epigenetic memory
Stem cells have the ability to remember the diverse experiences that they encounter throughout their lifetimes. Acute stimuli can thus have long-term repercussions on health and disease.
- Stem cells expand potency and alter tissue fitness by accumulating diverse epigenetic memories, Science 2021
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- Stem cells remember insults, Science 2021
- Cellular Memories — More Than Skin Deep, N Engl J Med 2022
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