STEM CELL BIOLOGY’S POTENTIAL IN REGENERATIVE MEDICINE
Embryonic stem cells for their pluripotency, the ability to give rise to all cell types in the body.
Adult stem cells for their innate ability to sense and respond to stresses in order to maintain functionality of their own tissue.
Fate transitions in pluripotent stem cells
From the various states of pluripotency to all its possible lineages, the manipulation of embryonic stem cell fate has become an invaluable device for fundamental discovery and disease modeling.
Epigenetic memory in tissue stem cells
Stem cells record past experiences within their chromatin, priming their response to future insults. How these memories interact with chronic disease and aging remains to be uncovered.